A Comprehensive Map of FDA-Approved Pharmaceutical Products

Comparison for Pharmaceutical Equivalence of FDA-Approved Products and Compounded Preparations... by S.D. Stanley et al.; P0634.1103

The potency and purity of compounded preparations of ketoprofen, amikacin, and boldenone were highly variable compared with Food and Drug Administration (FDA)-approved preparations of these drugs. These differences in concentration and purity could have important consequences for the efficacy and safety of the drug.

A Comprehensive Review of US FDA-Approved Immune Checkpoint Inhibitors in Urothelial Carcinoma

Few effective treatment options are available for patients with advanced or metastatic urothelial carcinoma (UC) after unsuccessful first-line platinum-based chemotherapy. To date, immune checkpoint inhibitors are novel therapeutic agents for UC treatment. From May 2016 to May 2017, five anti-PD-1/PD-L1 monoclonal antibodies received accelerated or regular approval from the US Food and Drug Adm...

FDA-Approved Drugs to Treat Schizophrenia.

FDA-approved medications that impair human spermatogenesis

We herein provide an overview of the single-ingredient U.S. Food and Drug Administration (FDA)-approved drugs that affect human spermatogenesis, potentially resulting in a negative impact on male fertility. To provide this information, we performed an in-depth search of DailyMed, the official website for FDA-approved drug labels. Not surprisingly, hormone-based agents were found to be the drugs...

FDA approved drugs as potential Ebola treatments

In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising in vitro activity. These compounds were not originally developed as antivirals and some have been further tested in mouse in vivo models. We put forward the opinion that some of these drugs could be evaluated further and move into the clinic as they are alread...